With the win, Fisher improves to 6-2 overall and 2-1 in the Empire 8.
The Cardinals led by just five at 23-18 after shooting just 26.7% over the opening 20 minutes, but scored the first 11 points of the second half and held the Tigers scoreless for the opening 5:46.
Stephanie Sweeney came through with an all-around performance, totaling eight points, eight assists and seven rebounds.
Fisher will return to action at 6 p.m. on Friday, as the Cardinals travel to Utica College for another Empire 8 contest.